Detecting evolutionary hot spots of antibiotic resistances in Europe

Program at a glance

Funding Agencies

European Science Foundation, European Commission

Program Period


Project Acronym


Project Code

COST Action TD0803

Project Title

Detecting Evolutionary Hot Spots of Antibiotic Resistances in Europe

Chair of the Action

Prof. Thomas Berendonk, TU Dresden, Germany

Vice Chair of the Action

Prof. Despo Fatta Kassinos, Nireas – International Water Research Center, University of Cyprus, Cyprus

Project Website


Program Overview

The main objective of DARE COST Action was to identify and characterize environmental hot spots for antimicrobial resistance (AR) emergence and spreading of antibiotics and antibiotic resistance patterns, aiming at the development of measures to control antibiotic resistance evolution. A network between medical researchers, urban water engineers, chemists, epidemiologists, microbiologists, environmental biologists and evolutionary biologists agreed on the following objectives: (a) assess the potential of wastewater treatment plants (UWTPs) and animal production as environmental hot spots for antimicrobial resistance emergence and spreading, (b) identify key processes, which foster or stabilize antibiotic resistances in different environments and assess measures to reduce the evolution of new AR, (c) develop an appropriate risk assessment and (d) identify key requirements for a (molecular) screening system of AR.

Dr. Despo Fatta-Kassinos was a member of the Management Committee and the Vice Chair of the Action.

Working Groups

WG1: Prevalence and spread of antibiotics and AR microbes
WG2: Antibiotics and AR microbes in UWTPs and animal production
WG3: Antibiotics and AR evolution in natural environments

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